Idiopathic thrombocytopenic purpura (ITP), happens to be one of the most common causes of symptomatic thrombocytopenia among children, which is an autoimmune-mediated hematologic disorder in which the destruction of platelets does occur thus resulting in isolated thrombocytopenia,
Causes of ITP
There is, in fact, an auto-immune reaction in one’s body by which antibodies are formed against platelets. These antibodies do get attached to the platelets and also flow in the bloodstream. Spleen, which does protect the body from infection, identifies these antibodies attached with platelets as abnormal as well as destroys them. As a result, the platelet count does get does result in easy bleeding as well as bruising on the body.
ITP may also be associated with people with infections like HIV, Hepatitis C or H pylori.
Signs and Symptoms of ITP
- Pinpoint bleeding spots (petechiae) on skin
- Easy bruising (purpura) on the skin and mucous membranes
- Bleeding from nose
- Bleeding from gums
- Heavy menstruation
- Prolonged bleeding from cuts or injuries
- Significant bleeding can lead to hematoma; lumps of blood under the skin
Diagnosis of ITP
The diagnosis is indeed usually made by excluding other underlying diseases or the use of certain medications such as Aspirin, Ibuprofen that are responsible for low platelet count as well as bleeding disorder.
A complete blood count (CBC) does, in fact, determine the value of platelets in the blood. In ITP, the value of RBC’s and WBC’s are in fact normal and only platelet count does get low.
Blood Smear –
This is done to confirm the platelet count by observing the blood smear under the microscope. One can detect antibodies that are associated with platelets in the blood.
Bone marrow biopsy or aspiration –
This is rarely done. In ITP, the bone marrow shows a normal or greater number of megakaryocytes (the early form of platelets). The platelets are indeed normal in the bone marrow and are destroyed in the bloodstream and in one’s spleen.
Splenomegaly (enlargement of the spleen) does exclude the diagnosis of ITP.
Treatment of ITP
Most of the children and adults with mild ITP do not require any treatment. A regular platelet count monitoring is sufficient to manage ITP.
However, in children and adults with very low platelet count and significant bleeding calls for treatment.
Oral or as to become the first choice of treatment for conventional doctors. However, prolonged usages of steroids are indeed responsible for side-effects such as osteoporosis, diabetes, weight gain, and cataract.
Intravenous Immunoglobulin (IVIG) in cases of severe bleeding, immunoglobulins when they have to be given intravenously does help to increase the platelet count rapidly but its effect does last only for a couple of weeks.
Platelet Transfusion helps in some cases of emergency but is helpful for a short period as the immune response of the body does destroy even the newly received donor platelets.
Anti-D immunoglobulin – for patients with Rh (D)-positive blood group.
Splenectomy in rare cases when a body is not responding to medications, removal of one’s spleen is done in order to prevent the destruction of platelets. The spleen is an organ which does help in protecting the body against infections so by removing the spleen the body does get more prone to infections.
Administering another immuno-suppressive drug
Homeopathic Treatment of ITP
Homeopathy can indeed be applied to treat various diseases and conditions such as cancer, allergy, mood disorders, headache, and pain. It can be used to treatment modality for idiopathic thrombocytopenic purpura (ITP), an autoimmune-mediated hematologic disorder
Homeopathic medicines are treatments of cortices steroid therapy and IVIg injection failed.
Homeopathic remedies can indeed be considered as complementary and alternative medicines for ITP treatment procedures on account of their mechanisms of action.
Best Homeopathy Treatment in Hyderabad can rather be cost-effective secondary or tertiary treatment modalities.